Metastasis – the process of cancer cells leaving the primary tumor and colonizing multiple organs – remains a major cause of cancer mortality. However, it is a highly inefficient process with only 0.01% of disseminated ...

Cellular differentiation is controlled by the complex dynamics of gene regulatory networks (GRNs), often featuring multistability, where multiple stable states represent different phenotypes. A common example is the toggle ...

To address the many unmet scientific needs in diabetes care (pathogenesis pathways, earliest diagnosis, efficient monitoring, safer and better therapies and importantly prevention approaches), our research focussed on: (a) ...

In the crowded confines of the eukaryotic cell, where large cargo (> 100 nm) are diffusionaly constrained, intracellular transport by motor proteins plays a crucial role in the exchange of material between various compartments ...

Optimal activation of immune cells is necessary to elicit a protective response against pathogens and foreign objects. In dysregulated immune systems, cells are aberrantly activated or exhausted. Understanding biochemical ...

The Indian Summer Monsoon is an important atmospheric phenomenon, marked by a characteristic seasonal wind reversal pattern, delivering 70 to 90% of the annual rainfall to the Indian subcontinent. Monsoon rain profoundly ...