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Production Of Anticancer Drug Taxol And Its Precursor Baccatin III By Fusarium Solani And Their Apoptotic Activity On Human Cancer Cell Lines
Taxol (generic name paclitaxel), a plant‐derived antineoplastic agent, was originally isolated from the bark of the Pacific yew, Taxus brevifolia. Obtaining taxol from this source requires destruction of trees. It has been ...
A Comparative Study On The Sensitivity Of Cells Of Different Lineages To Plant Ribosome Inactivating Protein - Abrin
Proteins with selective toxicity have been investigated for use in many ways. One class of proteins, ribosome-inactivating proteins (RIPs), is found throughout the plant kingdom as well as in lower organisms like certain ...
Glycodelin A : A Novel Immunoregulatory Lectin Of The Female Reproductive Tract : Molecular Mechanism Of GdA-Induced Apoptosis In Activated T Cells
Glycodelin is a 162 amino acid secreted glycoprotein classified as a member of the lipocalin (carriers of small hydrophobic molecules) superfamily based on the presence of lipocalin signature motifs in its primary sequence. ...
Type-II Ribosome Inactivating Proteins From Abrus Precatorius : Cytotoxicity And Mechanism Of Cell Death
Type-II Ribosome Inactivating Proteins from Abrus precatorius: Cytotoxicity and Mechanism of Cell Death A/B toxins produced by bacteria and plants are among the deadliest molecules known. The plant type-II ribosome ...
Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10
Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond. The toxicity of the protein comes from the A ...