Organic Chemistry (OC): Recent submissions
Now showing items 21-40 of 211
-
N-Heterocyclic Carbene (NHC)-Catalyzed Stereoselective Synthesis of Six-Membered Heterocycles and Carbocycles
N-Heterocyclic carbene (NHC) based catalysis is employed for the generation of α,β-unsaturated acylazoliums followed by their interception with various nucleophiles, the formal [3+3] annulation reactions for the construction ... -
Analytical Applications of Bile Acid-derived Soft Materials
Supramolecular gels are soft materials with solid-like properties such as supporting weight and retaining shape; and some liquid-like features which make them injectable, printable, etc. On the other hand, lanthanide-based ... -
Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds using Iodine and Zinc catalysts
The thesis entitled “Construction of Carbon-Heteroatom and Heteroatom-Heteroatom bonds using Iodine and Zinc catalysts” has been divided into five chapters. Chapter 1 describes a general introduction to iodine, hyper-valent ... -
Stereoselective synthesis of functionalized allenes, total synthesis of monticolides A and B, and towards the total synthesis of tulearin C
The thesis, entitled as “Stereoselective synthesis of functionalized allenes, Total synthesis of Monticolides A and B, and towards the total synthesis of Tulearin C” is divided into two chapters. Section A chapter-1 deals ... -
Design and Synthesis of New Delivery Vehicles for Anti- Cancer Therapeutics
The thesis entitled ‘‘Design and Synthesis of New Delivery Vehicles for Anti-Cancer Therapeutics’’ encloses the syntheses, characterization and bioactivity determination of the novel systems designed for achieving high ... -
Carbon-Carbon and Carbon Heteroatom Bond Forming Reactions: From Organocatalysts to Quantum Dots
Butenolides containing stereogenic centers on the ring, are commonly encountered structural motifs, found in many natural products. Consequently, there has been considerable interest in efficient and stereoselective ... -
Self-assembly of Luminescent Metal Nanoclusters, Supramolecular Bile salt based Gels and their Soft Nanocomposites
The thesis is based on the study of the self-assembly of multicolor luminescent nanoclusters, bile salt derived supramolecular gels and soft hybrid gel-nano composites -
Molecular Construction Using Carbene and Diboron Systems: Catalytic Transformation of C-C and C-Hetero Atom Bonds
The thesis presents an unconventional approach for the molecular construction using carbenes as the carbon source, and water as the hydrogen source. A gold-catalyst has been used to transfer the carbenes to effect ... -
Engineered Nanomaterials: Array-based Sensing of Biological and Chemical Analytes
Array-based sensing, also known as chemical nose/tongue analysis, offers an alternative platform for simultaneous differentiation of a wide range of analytes using a fixed number of cross-reactive receptors. The sensor ... -
Construction of C-C bonds by C-H Activation: Rh(III)-Catalyzed reactions of Arenes and Heteroarenes with Maleimides and Allylic Alcohols
The thesis presents a few Rh-catalyzed C-H activations for the construction of C-C bonds. The difficulty of substitution or the arylation at the maleimide's double bond under C-H activation conditions prompted a detailed ... -
Total synthesis of the macrolactone core of migrastatin, formal synthesis of (+)-ratjadone A, and towards the synthesis of sphingofungin F
The thesis entitled “Total synthesis of the macrolactone core of migrastatin, formal synthesis of (+)-ratjadone and Towards the total synthesis ofsphingofungin F” is divided into three chapters and an appendix highlighting ... -
Synthesis and Functionalization of Carbon and Sulfur-based Nanomaterials: Physical Properties and Molecular Recognition
In recent years carbon-based nanomaterials are growing rapidly in the field of science and technology, due to the tunable optical and physical properties such as electronic arrangement, photostability, flexibility and ... -
Sulfoximine and Sulfoxonium Ylide Directed C-H Activation and Domino Cyclization: Construction of Heterocyclic and Carbocyclic Rings
The thesis presents the construction of heterocyclic and carbocyclic rings using rhodium-catalyzed C-H bond activation followed by a tandem cyclization strategy. This involves the synthesis of heterocyclic compounds such ... -
Ru (II)-Catalyzed C−H Activation: Amide-Directed 1,4-Addition of Ortho C−H Bond to Maleimides
Transition metal catalyzed functionalization of C-H bond to C-C bond is advantageous and atom economical. The use of directing groups is intended to overcome the challenges associated with the C-H activation such as low ... -
Engaging Small Organic Molecules and Self-Assemblies for ‘Label-Free’ Recognition of Biologically Relevant Analytes
The thesis entitled ‘Engaging Small Organic Molecules and Self-Assemblies for ‘Label-Free’ Recognition of Biologically Relevant Analytes’ mainly deals with design and synthesis of various types of small molecular probes ... -
New Anthraquinone & Xanthone based Ligands as Potential Anti Cancer Agents via Selective Stabilization of G Quadruplex DNA and Theoretical Insights into G Quadruplex RNA Binding with Certain Small Molecules
In recent years, different small molecules have been synthesized for selective stabilization of G-quadruplex DNA structures over the most abundant double-stranded duplex DNA. Stabilization of G-quadruplex DNA by small ... -
Catalytic Asymmetric Direct and Vinylogous Aldol, Michael and Alkylation Reactions
Pyrazoles and pyrazolones are a highly explored and privileged class of aza-heterocycles with a wide range of applications, thereby rendering a recurring interest in their synthesis and functionalization. Majority of the ... -
Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding
Thesis titled, “Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding”, describes the development ... -
Synthetic Applications of C-2 Substituted Glucal
This report concerns the development of a synthetic approach towards synthesis of seven-membered septanosides, such as, substituted oxepanes from protected 2-hydroxyglycals. Important precursors to the synthesis of the ... -
Stereocontrol through Catalytic Enantioselective C(sp2)−H and C(sp3)−H Alkylation: From Bifunctional Organocatalysis to Iridium-Catalysis
This thesis, entitled “Stereocontrol through Catalytic Enantioselective C(sp2)−H and C(sp3)−H Alkylation: From Bifunctional Organocatalysis to Iridium-Catalysis” primarily deals with the development of various catalytic ...