Infectious diseases caused by pathogenic bacteria are creating a global health problem. In the recent report of World Health Organization (WHO), it has been mentioned that around 7 lacks people are dying each year worldwide ...

In chemical biology, short peptidomimetic biological active models have been widely used for anti-microbial activity, drug development, catalysis, and amyloidogenesis. In this thesis, I have synthesized several unnaturally ...

Conjugation of a carbohydrate moiety to an aromatic core leads to glycostructures that possess a high propensity for self-assembly in aq. solutions, driven primarily by π-stacking of the aromatic ring, as well as, the ...

Metal ions play indispensable roles across diverse processes, both biological and abiological, but their significance in the formation of complex self-assembled structures is only beginning to be understood. Sodium cholate, ...

The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri ...

Architecturally unique compounds produced by nature have remained a source of inspiration for organic chemists. Ladderane phospholipids (such as [5][3]PC and [3][3]PC), isolated in the year 2002 from anaerobic ammonium oxidizing ...

This thesis, entitled “Iridium-Catalyzed Enantioselective Alkylation of Enols and their Surrogates” is divided into four chapters. In Chapter 1, the examples of the utilization of vinyl azide as amide and ketone enolate ...

Delayed luminescence (DL) refers to light emission that persists after the excitation source is removed. Differing from conventional fluorescence, DL has a considerably longer lifetime attributable to the slow exciton ...

N-heterocyclic carbene (NHC)-catalyzed transformations with distinctive activation modes allow the facile synthesis of atropoisomers. In this context, we have demonstrated the NHC-catalyzed synthesis of axially chiral diaryl ...

Transition-metal and enzyme-catalyzed carbene insertion reactions are key methods for constructing C–X (X=N, O, S) and C–C bonds, primarily using catalysts such as Rh, Pd, Au, Cu, and Fe. While most of these give high ...