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Development of multifunctional polydimethylsiloxane-based polyurethanes as an ‘off-the-shelf’ alloplastic platform for urological reconstruction
Over 400 million patients suffer from urinary bladder-associated physiological disorders
globally, which often necessitate surgical intervention for a reconstructive procedure. The
current gold standard for bladder ...
Structural and Electrochemical Investigation of Bisulfate and Hydroxysulfate based Polyanionic Cathodes
The discovery of LiFePO4 cathode for Li-ion battery ushered intensive study on polyanionic high-voltage battery insertion materials. Polyanionic materials offer rich crystal chemistry, robust framework, voltage tunability, ...
Understanding the influence of electric field and dual doping on cytocompatibility of calcium phosphate bioceramics: Experimental and computational study
Although doped bioceramics have been widely investigated for biomedical applications, the co-doped bioceramics remain mostly unexplored for bone regeneration and dental applications. Given this background, we have successfully ...
Overcoming Challenges Associated with Designing of Thermoelectric Materials: DFT and Machine Learning Approaches
Search for clean and renewable energy resources has driven recent interest in designing thermoelectric materials that convert the waste heat to useful electricity. High performance thermoelectric materials require excellent ...
Engineered Nanomaterials: Array-based Sensing of Biological and Chemical Analytes
Array-based sensing, also known as chemical nose/tongue analysis, offers an alternative platform
for simultaneous differentiation of a wide range of analytes using a fixed number of cross-reactive
receptors. The sensor ...
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus
Design and Development of Proteasome Activity Modulators: A Novel Strategy for the Treatment of Diabetes Mellitus
Abstract
The ubiquitin-proteasome system (UPS) is the major pathway for degradation of the intracellular ...
Directing cellular differentiation using biophysical cues on multifunctional biomaterial platforms for neural and osteochondral applications
World health organization (WHO) has recognized multiple degenerative diseases as the leading causes of mortality, globally. The drugs-based clinical treatment of chronic degenerative diseases such as multiple sclerosis, ...
Identifying Bacterial Species, Detecting Antibiotic Resistance and Susceptibilities in Clinical Samples Using Raman Spectroscopy
Over the past few decades, Raman spectroscopy has found enormous applications in biology and medicine. Raman micro-spectroscopy is highly sensitive to the structure and composition of molecules and their surrounding moieties ...
Understanding quantitative process physics of 3D binderjet printing with validation in Ti-6Al-4V and inkjet bioprinting of mammalian cells
In the field of additive manufacturing, laser or electron beam based 3D printing is widely investigated for biomedical applications. However, much less explored is the binderjet 3D printing, which allows processing of ...
Development and Applications of Portable Raman Spectroscopy Combined with Artificial Intelligence for Biomedicine
Currently, the global spectroscopic community is investigating the suitability of vibrational spectroscopy methods for point-of-care testing, histopathology, and rapid in-vivo biomedical diagnostics. Although Raman ...