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Translational Control Of p53 And Its Isoform By Internal Initiation
Tumor suppressor p53, the guardian of the genome, has been intensely studied molecule owing to its central role in maintaining cellular integrity. While the level of p53 protein is maintained low in unstressed conditions, ...
Starvation Response In Mycobacterium Smegmatis : A Tale Of Two Proteins
The Dps (DNA-Binding Protein from Starved Cells) proteins are a class of stress-specific proteins with a major role in protecting DNA during the stationary phase of bacterial growth, through direct physical binding as well ...
Molecular Actions Of Arecoline, An Alkaloid Implicated In The Manifestation Of Oral Submucous Fibrosis (OSMF)
The pathogenesis of oral submucous fibrosis (OSMF) is due to a complex interplay between the production and degradation of extracellular matrix (ECM) protein components. In tissue fibrosis, there is a net accumulation of ...
Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners
PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ...
T Cell Epitopes Of PE And PPE Family Of Proteins Of Mycobacterium Tuberculosis And Analysis Of Their Vaccine Potential
One-third of the world’s population is latently infected with Mycobacterium tuberculosis, which causes over 2 million deaths every year. The current live attenuated vaccine, Bacille Calmette-Guerin (BCG), protects against ...