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Targeting The CD4 Biniding Site In HIV-1 Immunogen Design
(2016-11-15)
Over three decades have passed since the discovery of HIV-1, yet an AIDS vaccine remains elusive. The envelope glycoprotein of HIV-1 gp120, is the most exposed protein on the viral surface and thus serves as an important ...
Lithium Exposure Induced Changes At Glutamatergic Synapses In Hippocampal Neurons- Insights From In Vitro Electrophysiology And Imaging Studies
(2016-11-15)
Lithium is a drug used to treat mood disorders and also has many side effects, including central nervous system (CNS) complications (such as cognitive dulling), associated with its use. The mechanism of its action still ...
Insights Into The Mechanism Of Actions Of Luteinizing Hormone And Prostaglandin F2α In The Regulation Of Corpus Luteum Function Of Monoovulatory Species
(2016-11-11)
Corpus luteum (CL), a transient endocrine structure formed from the ruptured ovarian follicle after ovulation, secretes progesterone (P4) that is essential for establishment and maintenance of pregnancy in mammals. The ...
Insights Into Cytostatic Mechanisms Regulated By Receptor Guanylyl Cyclase C
(2016-11-16)
All cells are equipped to sense changes in their environment and make adaptive responses according to the stimuli. Signal recognition usually occurs at the cell membrane (with the exception of steroid signalling) where the ...
Spatio-Temporal Control Of Drosophila Indirect Flight Muscle Development And Maintenance By The Transcription Factor Erect Wing
(2016-04-27)
Muscle development involves concerted action of a repertoire of mechanisms governing myoblast proliferation, migration, fusion and differentiation. Subsequently, there are cellular events administrating proper muscle ...
Role Of Insulin-Like Growth Factors Binding Protien 2 (IGFBP2) In Breast Cancer
(2016-04-27)
Insulin-like growth factor binding proteins (IGFBPs) modulate the bioavailability of IGFs in circulation. IGFBPs 1-6 bind IGFs with high affinity and can either potentiate or inhibit IGF signaling in a context dependent ...
Insights Into The Trans-Splicing Based Expression Of Heat Shock Protein 90 In Giardia Lamblia
(2016-09-14)
Heat shock proteins (Hsps) are a class of molecular chaperones which were first discovered as proteins up-regulated in response to heat stress in Drosophila. Later, it was found that these set of proteins get up-regulated ...
Determinants Of Behavioural And Reproductive Dominance In The Primitively Eusocial Wasp Ropalidia Marginata
(2016-09-15)
In societies where all individuals are reproductively totipotent and yet, at a given time only one of them reproduces, it is interesting to examine the factor(s) that may influence and predict who will be the reproductive. ...
The Distribution, Dynamics & Impacts Of Invasive Lantana Camara In A Seasonal Forest Of Mudumalai, Southern India
(2016-04-25)
Species that become naturalized in a new geographical range, subsequently multiply and spread, and persist to the detriment of resident communities, are known as alien invasive species. Two aspects of species invasion – ...
Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication
(2016-04-28)
Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae ...