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Molecular Characterization c-di-GMP Signalling In Mycobacterium Smegmatis
(2014-07-17)
Bacterial stationary phase is an interesting biological system to study, as the organism undergoes several metabolic changes during this period and new molecules are generated to support its survival. The stationary phase ...
Structure Analysis Of Plant Lectin Domains
(2014-04-07)
Lectins are multivalent carbohydrate binding proteins that specifically recognise diverse sugar structures and mediate a variety of biological processes, such as cell-cell and host-pathogen interactions, serum glycoprotein ...
Studies On The Mechanism Of Uracil Excision Repair In Escherichia Coli And Structure-Function Relationship Of Single Stranded DNA Binding Proteins From Escherichia Coli And Mycobacterium Tuberculosis
(2014-12-11)
To maintain the genomic integrity, cell has evolved various DNA repair pathways. Base Excision Repair pathway (BER) is one such DNA repair pathway which is dedicated to protect DNA from small lesions such as oxidation, ...
Metallophosphoesterases In Mycobacteria Enigmatic Roles In Regulating Mycobacterial Physiology
(2014-04-29)
Pathogenic bacteria such as M.tuberculosis have evolved several mechanisms to aid their intracellular survival and subvert host defenses. One of the contributing factors is thought to be the production and secretion of ...
Insights Into The Contribution Of Hfq In Salmonella Pathogenesis : Possible Role In Immune Evasion And Vaccine Development
(2014-10-07)
Chapter I Introduction Salmonellae are facultative Gram-negative intracellular pathogens. Different serovars of it causes a variety of diseases in multiple hosts with different disease outcomes. Salmonella enterica serovar ...
Identification Of GAL102 Encoded UDP-Glucose 4, 6 Dehydratase Activity, As A Novel Virulence Factor In Candida Albicans
(2014-08-11)
Among fungal pathogens responsible for opportunistic infections, species of the genus Candida have a major role (Mitchell, 1998). Various Candida species cause superficial infections which can be cured by the currently ...
Climate Change Mitigation And Adaptation In Indian Forests
(2014-10-10)
Research leading to this thesis aims to assess the policy relevant mitigation potential of Indian forests as well as aims to assess the impact of climate change on carbon stocks, vegetation boundary shifts, Net Primary ...
Structural Studies Of E. Coli Thioredoxin And P. Falciparum Triosephosphate Isomerase By NMR And Computational Methods
(2014-05-21)
To unravel the mysteries of complex biological processes carried out by biomolecules it is necessary to adopt a multifaceted approach, which involves employing a wide variety of tools both computational and experimental. ...
Computational And Experimental Studies On Protein Structure, Stability And Dynamics
(2014-08-18)
The work in this thesis focuses on the study of three main aspects of proteins, viz, Protein structure, stability, and dynamics. Chapter 1 is a general introduction to the topics studied in this thesis. Chapter 2 deals ...
Trade-offs And Social Behaviour In The Cellular Slime Moulds
(2014-08-01)
By combining laboratory experiments with field work, I have looked at the following aspects of cellular slime mould (CSM) biology: (a) the genetic structure of social groups (fruiting bodies) in the wild and its relation ...