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Structural Studies On Mycobacterial RecA And RuvA
(2010-10-21)
Homologous recombination is a fundamental cellular process evolved to maintain genomic integrity and to generate genetic diversity. It plays a crucial role in DNA repair, correct segregation of meiotic chromosomes and ...
Computational Analyses Of Proteins Encoded In Genomes Of Pathogenic Organisms : Inferences On Structures, Functions And Interactions
(2015-02-04)
The availability of completely sequenced genomes for a number of organisms provides an opportunity to understand the molecular basis of physiology, metabolism, regulation and evolution of these organisms. Significant ...
Insights Into The Mechanistic Details Of The M.Tuberculosis Pantothenate Kinase : The Key Regulatory Enzyme Of CoA Biosynthesis
(2013-04-26)
Tuberculosis (TB), caused by Mycobacterium tuberculosis, has long been the scourge of humanity, claiming millions of lives. It is the most devastating infectious disease of the world in terms of mortality as well as morbidity ...
Regulation of Leaf Margin Development by TOOTH/MIR160A in Arabidopsis Thaliana
(2017-11-13)
TOOTH/MIR160A regulates leaf margin outgrowth in Arabidopsis thaliana
Unlike animals, a striking aspect of the plant development is that they have evolved a flexible pattern of post embryonic development. This exposes ...
Functional Characterization of Saccharomyces Cerevisiae SUB1 in Starvation Induced Sporulation Response
(2017-12-12)
Among the various external signals perceived by yeast cells, nutrient availability is a condition to which these cells show a highly diverse biological response. Diploid cells in response to different nutritional stress ...
Peroxisomal Targeting Of Pichia Pastoris Cytochrome C During Methanol And Fatty Acid Metabolism
(2011-03-08)
Intracellular protein sorting plays a key role in the regulation of cellular metabolism, gene expression, signal transduction and a number of other cellular processes. Proteins targeted to specific cellular compartments ...
Identification And Characterisation Of Two Silencing Barrier Sequences In Saccharomyces Cerevisiae
(2010-07-21)
In eukaryotic cells, genomic DNA exists as chromatin in association with histone octamers called nucleosomes, and various other chromatin proteins. Chromatin structure varies along the chromosome and this influences the ...
Topoisomerases from Mycobacteria : Insights into the Mechanism, Regulation and Global Modulatory Functions
(2018-03-09)
The eubacterial genome is maintained in a negatively supercoiled state which facilitates its compaction and storage in a small cellular space. Genome supercoiling can potentially influence various DNA transaction processes ...
DNA Repair Proteins in Mycobacteria and their Physiological Importance
(2018-03-09)
DNA repair proteins in mycobacteria and their physiological importance
Mycobacterium tuberculosis, the causative organism of tuberculosis, resides in the host macrophages where it is subjected to a plethora of stresses ...