Browsing Division of Biological Sciences by Title
Now showing items 401-420 of 1019
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Intracellular Calcium Dynamics In Dendrites Of Hippocampal Neurons Rendered Epileptic And In Processes Of Astrocytes Following Glutamate Pretreatment
(2009-04-03)The fundamental attribute of neurons is their cellular electrical excitability, which is based on the expression of a plethora of ligand- and voltage-gated membrane channels that give rise to prominent membrane currents ... -
Intrasexual competition in females of a socially polygynous lizard, Psammophilus dorsalis
Competition between individuals of the same sex, intrasexual competition, has received much attention in males, mainly because such competition, which is primarily for mates (i.e. sexual selection), often selects for ... -
Intrinsic Noise in Collective Dynamics
Animal groups exhibit many emergent properties that are a consequence of local interactions. Linking individual-level behaviour to group-level dynamics has been a question of fundamental interest from both biological and ... -
Intrinsic Versus Induced Variations In DNA Structure
(2011-07-18)The binding of different proteins involved in processes such as transcription, replication and chromatin compaction to regions of the genome is regulated by the structure of DNA. Thus, DNA structure acts as the crucial ... -
Invertase in a thermophilic fungus, thermomyces lanuginosus: its unusual behaviour And regulation
(Indian Institute of Science, 2005-04-25)The understanding of the phenomenon of thermophily requires investigations of both thermophilic prokaryotes and eukaryotes. In the eukaryotes, thermophily is exhibited only by a few species of fungi which can grow up to ... -
Investigating DNA structural basis for fragility during chromosomal translocations associated with human B-cell lymphomas
Genome integrity is essential for normal cellular functions. Erroneous repair of DNA double-strand breaks (DSBs) could lead to chromosomal rearrangements, including chromosomal translocations that may result in altered ... -
Investigating mechanisms underlying astrocytic involvement in depressive-like behavior and antidepressant action
Major Depressive disorder (MDD) is a complex, multifactorial psychiatric illness which affects over 20% of the population worldwide. Despite its prevalence, our understanding of its pathophysiology is severely limited, ... -
Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development
Title: Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development The classic ABCDE model for floral organ identity show that ... -
Investigating Pattern Recognition And Bi-coordinate Sound Localization in the Tree Cricket Species Oecanthus Henryi
(2017-09-20)Acoustic communication, used by a wide variety of animals, consists of the signaler, the signal and the receiver. A change in the behaviour of the receiver after reception of the signal is a prerequisite for communication. ... -
Investigating the Impact of Habitat Disturbance and the Role of Functional Traits in a Tropical Butterfly Assemblage
(2018-07-09)Tropical habitats face a diverse range of anthropogenic threats. Two common and important threats to tropical biodiversity are invasive species and roads. Invasive plants are proposed to be a major threat to biodiversity ... -
Investigating the mechanisms of cancer drug resistance
Clinical chemo-resistance has posed a challenge to scientists and clinicians since the development of chemotherapeutics as anticancer strategy. Mechanisms of drug resistance continue to be a subject investigation amongst ... -
Investigating the Novel Roles of miR-9a and the Regulators of Mitochondrial Dynamics During the Development and Functioning of Indirect Flight Muscles in Drosophila melanogaster
The muscular system is a highly complex and important system in the body. Proper muscle physiology is critical for locomotion, digestion, circulation, reproduction as well as for metabolic and immune homeostasis. Defects ... -
Investigating the redox signaling mechanisms during HIV-TB co-infection
Oxidative stress has been at the forefront of HIV/AIDS-related pathophysiologies since the early days of its discovery. Overcoming HIV-1 latency, wherein, the virus remains integrated in the host chromatin, undetected and ... -
Investigating the role and regulation of Polypyrimidine tract binding protein (PTB) in isoform switching during muscle development in Drosophila melanogaster
Muscles are an excellent system to dissect the development, physiology and evolution of cell heterogeneity and isoform switching. The vertebrate skeletal muscles are composed of heterogeneous muscle fibres. These fibres ... -
Investigating the role of AMPK in mammary gland alveologenesis and lactation
AMP-activated kinase (AMPK) is an energy sensor that regulates cell growth and metabolism. Reports from our laboratory and others have shown the context-specific role of AMPK signaling in breast cancer. However, its role ... -
Investigating the role of an atypical dual-specificity phosphatase DUSP28 in mammalian cells
Dual-specificity phosphatases (DUSPs) belong to the protein tyrosine phosphatases (PTP) subfamily and dephosphorylate, both serine/threonine and tyrosine residues of proteins and non-protein substrates. A subgroup of ... -
Investigating the role of miR-198 in oral squamous cell carcinoma pathogenesis
Evidence supports the critical role of microRNA (miRNA) dysregulation in several diseases including cancers. The aberrant expression of numerous tumor suppressor and oncogenic miRNAs is a well-established driving factor ... -
Investigating the role of taxi gene in flight behavior of Drosophila melanogaster
Locomotion is essential for animals and it is regulated by crosstalk between neurons and muscles. Although defects in the crosstalk between neurons and muscles are implicated in many mobility related diseases in human, ... -
Investigation of anticancer compounds in the natural productome of marine algae associated-endophytic fungi
Cancer is one of the leading causes of death worldwide. Owing to the complex ways in which this disease develops, there is a constant demand for new drugs. Natural products have delivered great promise in inspiring ...