Browsing by Subject "Abrin"
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A Comparative Study On The Sensitivity Of Cells Of Different Lineages To Plant Ribosome Inactivating Protein - Abrin
(2010-12-08)Proteins with selective toxicity have been investigated for use in many ways. One class of proteins, ribosome-inactivating proteins (RIPs), is found throughout the plant kingdom as well as in lower organisms like certain ... -
Crystal Structure Of Abrus Precatorius Agglutinin-I (APA-I) : Insights Into The Reduced Toxicity Of APA-I In Relation To Abrin. Formation Of Ordered Nanotubes Through Self Assembly In The Crystal Structures Of Dipeptides Containing α. β-dehydrophenylalanine
(2009-07-22)Ribosome Inactivating Proteins (RIPs) are protein or glycoprotein toxins that bring about the arrest of protein synthesis by directly interacting with and inactivating the ribosomes. Such toxins are in general, of plant ... -
Immunoneutralization Of Cytotoxic Abrin : Insights Into Mechanisms And Therapy
(2015-12-02)Type II Ribosome Inactivating Proteins (RIPs), commonly known as A/B toxins are heterodimers comprising of a catalytically active A chain, an RNA N-glycosidase which inhibits protein synthesis and a lectin-like B chain ... -
Insights into the Differential Cytotoxicity of Abrin and Design of a Vaccine Candidate against the Toxin
Ribosome inactivating proteins (RIPs) from plants, fungi or bacteria are extremely lethal due to their N-glycosidase activity on eukaryotic ribosomal RNA. As the name indicates, these toxins inactivate ribosomes; thereby ... -
Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10
(2017-11-23)Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond. The toxicity of the protein comes from the A ... -
Type-II Ribosome Inactivating Proteins From Abrus Precatorius : Cytotoxicity And Mechanism Of Cell Death
(2009-05-21)Type-II Ribosome Inactivating Proteins from Abrus precatorius: Cytotoxicity and Mechanism of Cell Death A/B toxins produced by bacteria and plants are among the deadliest molecules known. The plant type-II ribosome ...