Browsing by Title
Now showing items 4634-4653 of 6370
-
Role of Lactate and TREK1 Channels in Neuroprotection during Cerebral Ischemia – in Vitro Study in Rat Hippocampus
(2017-12-16)Cerebral ischemia is a highly debilitating condition where shortage of oxygen and glucose leads to profuse cell death. Insufficient blood supply to the brain leads to cerebral ischemia and increase in extracellular lactate ... -
The Role of Liposomal Hybrids and Gold Nanoparticles in the Efficacious Transport of Nucleic Acids and Small Molecular Drugs for Cancer Nanomedicine
(2018-07-23)The thesis entitled “The Role of Liposomal Hybrids and Gold Nanoparticles in the Efficacious Transport of Nucleic Acids and Small Molecular Drugs for Cancer Nanomedicine” elucidates the preparation of various liposomal ... -
Role of Lysyl oxidase in TGF-beta-induced Fibroblast Activation and Cancer-Associated Fibroblast-mediated Breast Cancer Progression
Cancer-associated Fibroblasts (CAFs) are a dominant cell type of the breast cancer microenvironment and are proposed to be involved in metastatic progression. TGF-β has been reported to influence fibroblast to myofibroblast ... -
Role of Mammalian RAD51 Paralogs in Genome Maintenance and Tumor Suppression
(2018-01-28)My research was focused on understanding the importance of mammalian RAD51 paralogs in genome maintenance and suppression of tumorigenesis. The investigation carried out during this study has been addressed toward gaining ... -
Role of mammalian RAD51 paralogs in replication stress response and genome maintenance
The focus of my research has been to understand the molecular mechanisms underlying the role of mammalian RAD51 paralogs in genome maintenance and tumor suppression. The investigation carried out during this study has ... -
Role Of Matrix Protein Of Rinderpest Virus In Viral Morphogenesis
(2008-10-20)Rinderpest virus is an enveloped Nonsegmented Negative Stranded RNA Virus (NNSV) belonging to the genus Morbillivirus in the Family Paramyxoviridae and the causative organism for “cattle plague”. The virion has a transport ... -
Role of Microstructure in the Mechanics of Soft Matter
(2018-07-16)Materials which exhibit non-linear mechanical behaviors under large deformations are generally classified as “soft matter”. Elastomers represent an important class of soft materials which have wide commercial applications ... -
Role of Mint family of Proteins in the nanoscale localization and real-time retention of surface Amyloid Precursor
Amyloid beta, a key determinant in the pathology of Alzheimer's disease (AD), is formed by the sequential proteolysis of Amyloid Precursor Protein (APP) by β-and γ-secretase. Evidence over the last few decades indicates ... -
Role Of Mixed Convection In Cooling Of Electronics
(2011-03-15)Cooling of electronic components is one of the most important issues concerned in the electronic industry for design of equipment. Maintaining the temperature of an electronic device within its safe operating temperature ... -
Role of Mycobacterium tuberculosis DinG and UvrD helicases in unwinding G-quadruplex DNA
Recent studies have demonstrated the role of E. coli UvrD as a replicative helicase that facilitates replication of rolling circle plasmids. Along with dinG and rep helicase, UvrD a so-called “accessory helicase” removes ... -
Role of Mycobacterium Tuberculosis RecG Helicase in DNA Repair, Recombination and in Remodelling of Stalled Replication Forks
(2018-05-14)Tuberculosis, caused by the infection with Mycobacterium tuberculosis remained as a major global health challenge with one third of world population being infected by this pathogen. M. tuberculosis can persist for decades ... -
Role of Mycobacterium tuberculosis UvrD1 and UvrD2 helicases in resolving G-quadruplex DNA structures
Unresolved G-quadruplex (G4) DNA secondary structures impede DNA replication and can lead to DNA breaks and to genome instability. Helicases are known to unwind G4 structures and thereby facilitate genome duplication. ... -
Role of Nonlocality and Counterfactuality in Quantum Cryptography
(2018-01-09)Quantum cryptography is arguably the most successfully applied area of quantum information theory. In this work, We invsetigate the role of quantum indistinguishability in random number generation, quantum temporal ... -
The Role of Nursery Size and Plant Phenology on the Reproduction of and Relationships within a Fig-fig Wasp Nursery Pollination System
(2018-05-09)Obligate nursery pollination mutualisms such as the fig–fig wasp system, with their central plant–pollinator mutualism associated with non-pollinating satellite wasp species, can function as closed system microcosms ... -
Role of Oxygen Vacancies in Modification of Electronic Structure of Bulk Oxides
Emergent phenomena in oxides have been receiving a lot of experimental and theoretical interest in the recent decade. In general, oxides host a rich diversity of defects and several new emergent phenomena such as 2-DEG ... -
Role of Physico-chemical Processes And Micro-structural Features in Influencing Moisture Loss and Engineering Properties Of Compacted Residual Soils Exposed To Environmental Relative Humidity
The moisture content of residual soils above the water table, and near ground surface (≤ 6 m) is influenced by the environmental relative humidity (RH). The focus of this thesis is to examine the physico-chemical and ... -
The role of polymer phase on rigidity percolation of ABS−spherical nickel microparticles composites
Percolation and rigidity transitions are very important phenomena in random heterogeneous microstructures, as various physical properties change abruptly at some critical volume fractions of one phase. The concepts of ... -
The Role Of Potential Theory In Complex Dynamics
(2014-04-07)Potential theory is the name given to the broad field of analysis encompassing such topics as harmonic and subharmonic functions, the Dirichlet problem, Green’s functions, potentials and capacity. In this text, our main ... -
Role of Power Control in Enhancing the Performance of Opportunistic Selection Schemes
Opportunistic selection reaps the benefits of multiuser diversity in many wireless applications. For example, it increases throughput of cellular networks, lifetime of wireless sensor networks, and improves diversity in ...